Antidepressants Cause Autism-Like Gene Expression in Fish

von freakoutcrazy

Prozac, Effexor, and/or carbamazepine induce gene expression patterns in the brains of fathead minnows that mimic those thought to be associated with autism in humans, according to a study published yesterday (June 6, 2012) in PLoS One. The study found that the pattern of gene expression was specific to idiopathic (heredity x environment) autism, but not other autism diagnoses associated with specific mutations. The authors write that the findings are consistent with a theorized role of elevated serotonergic neurodevelopmental perturbations during pregnancy that may be associated with a dramatic increase of idiopathic autism.

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